Hogan A Porta Di Roma

PR3 also called myeloblastin, specifically expressed by neutrophils and monocytes, belongs to the neutrophil serine protease family and is classically localized in azurophilic granules with its homologs: elastase, cathepsin G and azurocidin. After phagocytosis of pathogens, PR3 is secreted in the phagolysosome to play its microbicidal function. Although PR3 shares more than 60% sequence homology […]

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